FAMP
Adjuvant treatment of early breast cancer, 1st and 2nd line treatment of Advance Breast Cancer.
Molecules
Letrozole Tablet
Therapeutic Class
Aromatase Inhibitor
Strength
2.5 mg
Doses
"Breast cancer - 2.5 mg orally each day, until tumor progression evident Ovarian Epithelial Cancer 2.5 mg orally each day. For infertility :The most common dose is 2.5 mg per day on days five through nine of the menstrual cycle. Sometimes it is given in higher doses of 5 mg or 7.5 mg per day"
Indications
Breast cancer (in postmenopausal women), infertility
Side Effects
"The observed adverse reactions are mainly mild or moderate in nature, and most are associated with estrogen deprivation. The most frequently reported adverse reactions are hot flushes, arthralgia, nausea and fatigue."
Contradictions
Hypersensitivity. Premenopausal endocrine status. Pregnancy & lactation
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